Discovery May Lead To New Approaches To Cancer, Neurodegeneration, Growth Defects And Diabetes

Tweet Cells develop and thrive by turning genes on and off as needed in a precise pattern, a process known as regulated gene transcription. In a paper published in the Journal of Neuroscience, researchers at the University of California, San Diego School of Medicine say this process is even more complex than previously thought, with regulated genes actually relocated to other, more conducive places...
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Bacteria in the mouth of man, to help doctors detect cancer

Tweet Normal saliva may be key to the diagnosis of pancreatic cancer by a new method developed by a team of scientists led by James Farrell of the University of California, says New Scientist. It offers a look at some salivary bacteria. The researchers specifically compared the bacteria in the saliva of 10 healthy people with samples taken from patients with pancreatic cancer. They found a large...
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Link Found Between Biological Agents For Rheumatoid Arthritis And Greater Skin Cancer Risk

Tweet A systematic review published in the Annals of the Rheumatic Diseases suggests, that biological agents used for the treatment of rheumatoid arthritis seem to be linked with an increased risk of skin cancer. Inflammatory arthritis has been associated with an increased risk of some types of cancers, in particular with lymphoma and lung cancer but with a lower risk of other cancer types, such as...
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Positive Results From Phase 2 Clinical Study Of NKTR-102 In Metastatic Breast Cancer Presented In Oral Session At The ASCO 2011 Symposium

Tweet Nektar Therapeutics (Nasdaq: NKTR) announced that positive results from the company’s Phase 2 clinical study of NKTR-102 in patients with metastatic breast cancer were presented at the ASCO 2011 Breast Cancer Symposium in San Francisco, California. NKTR-102 is a novel topoisomerase I inhibitor designed using Nektar’s proprietary polymer conjugate technology, and is being developed...
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Walnuts Reduce Breast Cancer Risk By Half In Animal Studies

Tweet Mice fed a diet that included daily walnuts had half the risk of developing breast cancer compared to those on a typical diet, researchers from Marshal University School of Medicine reported in the journal Nutrition and Cancer. Elaine Hardman, Ph.D. and team set out to determine what impact the inclusion of a moderate amount of walnuts in the animals’ daily diet might have on their breast...
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Modified Ecstasy Compounds Have Powerful Anti-Cancer Properties

Tweet Altered forms of MDMA (Ecstasy) which are 100 times better at destroying cancer cells could be used to effectively treat patients with leukemia, lymphoma, and myeloma, according to an article in Investigational New Drugs. The authors, from the University of Birmingham, UK, explained that while Ecstasy is already known to have anti-cancer qualities, these modified forms of the drug are 100 times...
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Melanoma Drug, Vemurafenib, Approved By US FDA

Tweet The drug vemurafenib (Zelboraf) for metastatic melanoma in patients who test positive for the BRAF mutation, has been approved by the U.S. Food and Drug Administration. Vemurafenib, a BRAF-inhibitor, is a personalized investigational drug designed to specifically inhibit the activity of the mutant BRAF protein that is present in almost half of all melanoma cases, the most lethal and aggressive...
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New Study Explores Immune System Stimulation In Battle Against HER-2/neu Positive Breast Cancer

Tweet The Mayo Clinic is excited to announce a Phase I study of a new therapeutic vaccine in HER-2/neu positive breast cancer patients in the fourth quarter of 2011. To understand the importance of this development, the HER-2/neu and the significance of HER-2/neu positive breast cancer must be examined. Due to a genetic change, cancerous cells produce an excess of HER2 in approximately 1 in 5 breast...
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Building A Better Sunscreen; Just Add Caffeine Or Drink Coffee?

Tweet New research has found that in the route to building a better sunscreen, caffeine may be the key. Caffeine has been found to change the activity of a gene involved in the destruction of cells that have DNA damage and are therefore more likely to become cancerous. Allan Conney of the department of chemical biology at Rutgers University tested the idea by creating genetically modified (GM) mice...
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Study Shows Annual Cervical Cancer Screening Still Recommended By Most Primary Care Providers Despite Suggested Guidelines

Tweet Researchers from the Centers of Disease Control and Prevention (CDC) have determined that most primary care providers still recommend annual cervical cancer screening, and less than 15% would extend the screening interval when using the Papanicolaou test and human papillomavirus (HPV) test together, as some guidelines suggest. The results of the investigation are published online today in the...
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